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Effect of reducing ambulance response times on deaths from
out of hospital cardiac arrest: cohort study
BMJ 2001;322:1385-1388 ( 9 June )
Entire article, with discussion is at http://www.bmj.com/cgi/content/full/322/7299/1385
Jill P Pell
, honorary clinical senior lecturer, a
Jane M Sirel
, research assistant, a
Andrew K Marsden
, medical director, b
Ian Ford
, professor of statistics, c
Stuart M Cobbe
, Walton professor of medical cardiology. a
a Department of Medical Cardiology,
University of Glasgow, Glasgow Royal Infirmary, Glasgow G31 2ER, b Scottish
Ambulance Service Headquarters, Edinburgh, c Robertson Centre
for Biostatistics, University of Glasgow
Correspondence to: S M Cobbe stuart.cobbe@clinmed.gla.ac.uk
Objectives: To determine the
association between ambulance response time and survival from out of
hospital cardiopulmonary arrest and to estimate the effect of
reducing response times.
Design: Cohort study.
Setting: Scottish Ambulance Service.
Subjects: All out of hospital cardiopulmonary arrests due to
cardiac disease attended by the Scottish Ambulance Service during May
1991 to March 1998.
Main outcome measures: Survival rate to hospital discharge and potential
improvement from reducing response times.
Results: Of 13 822 arrests not witnessed by ambulance crews
but attended by them within 15 minutes, complete data were available
for 10 554 (76%). Of these patients, 653 (6%) survived to
hospital discharge. After other significant covariates were adjusted
for, shorter response time was significantly associated with
increased probability of receiving defibrillation and survival to
discharge among those defibrillated. Reducing the 90th centile for
response time to 8 minutes increased the predicted survival to
8%, and reducing it to 5 minutes increased survival to 10-11% (depending
on the model used).
Conclusions: Reducing ambulance response times to 5 minutes could
almost double the survival rate for cardiac arrests not witnessed by
ambulance crews.
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What is already known on
this topic
Three quarters of all deaths from myocardial infarction occur after
cardiac arrest in the community
Survival after out of hospital arrest is
much lower in the United Kingdom than the United States
What this study adds
Ambulance response times are independently associated with
defibrillation and survival
Decreasing the target for response to 90% of
calls from 14 minutes to 8 minutes would increase survival
from 6% to 8%
A response time of 5 minutes would
increase survival to 10-11%
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